Acanthamoeba Keratitis (AK)

12 min read

Acanthamoeba Keratitis (AK) is a rare but serious eye infection caused by a microscopic, free-living amoeba. It is most commonly found in warm, fresh water, such as lakes, rivers, and hot tubs, and can also be found in soil and air. AK is a sight-threatening infection that can cause permanent vision loss if not treated promptly and correctly.

Causes of Acanthamoeba Keratitis

AK is caused by the Acanthamoeba amoeba, which is found in many environments. It is most commonly contracted when contaminated water or soil comes into contact with the eye. This can happen when swimming in contaminated water, wearing contact lenses, or using contaminated contact lens solution. It can also occur when a person is exposed to contaminated dust or soil.

Diagnosis of Acanthamoeba Keratitis

AK is difficult to diagnose because its symptoms are similar to other eye infections. A doctor may suspect AK if a patient has a history of contact with contaminated water or soil, or if they wear contact lenses. To confirm the diagnosis, a doctor may take a sample of the eye’s fluid and examine it under a microscope. They may also take a culture of the eye’s fluid to identify the amoeba.

Prevention of Acanthamoeba Keratitis

The best way to prevent AK is to avoid contact with contaminated water or soil. People who wear contact lenses should take extra precautions, such as using only sterile contact lens solution and cleaning their lenses regularly. People should also avoid swimming in warm, fresh water, such as lakes and rivers.

Take the Acanthamoeba Keratitis (AK) Assessment

Symptoms

Early Symptoms of Acanthamoeba Keratitis

Early symptoms of AK may include redness, pain, light sensitivity, and blurred vision. These symptoms may be mild at first and may come and go. As the infection progresses, the symptoms may become more severe and persistent.

Advanced Symptoms of Acanthamoeba Keratitis

Advanced symptoms of AK may include a feeling of something in the eye, a corneal ulcer, or scarring of the cornea. In some cases, the infection can cause vision loss. If you experience any of these symptoms, it is important to seek medical attention immediately.

Diagnosis of Acanthamoeba Keratitis

If you experience any of the symptoms of AK, it is important to seek medical attention immediately. Your doctor will perform a thorough eye exam and may take a sample of your eye fluid for testing. Treatment for AK typically involves the use of antibiotics and other medications.

Prevention of Acanthamoeba Keratitis

The best way to prevent AK is to take precautions when using contact lenses. Always wash your hands before handling your lenses, and never wear them while swimming or in hot tubs. Be sure to replace your lenses as recommended by your doctor, and never share them with anyone else.

Causes

Contact Lens Use

One of the most common risk factors for AK is contact lens use. The amoeba that causes AK is found in water, soil, and air, and can contaminate contact lenses and their storage cases. Poor contact lens hygiene, such as not cleaning and replacing lenses as recommended, can increase the risk of AK. Wearing contact lenses while swimming or in hot tubs can also increase the risk of infection.

Eye Injury

Eye injuries, such as scratches or abrasions, can also increase the risk of AK. These injuries can provide an entry point for the amoeba to enter the eye and cause infection.

Immune System

People with weakened immune systems, such as those with HIV/AIDS or those undergoing chemotherapy, may be more likely to develop AK. This is because their immune systems are not as effective at fighting off infection.

Environmental Factors

Environmental factors, such as exposure to contaminated water or air, may also increase the risk of AK. People who live in areas with poor water quality or who work in dusty or dirty environments may be more likely to develop the infection.

Conclusion

Acanthamoeba keratitis is a rare but serious eye infection that can cause permanent vision loss if not treated promptly and correctly. While the exact cause of AK is unknown, contact lens use, eye injuries, weakened immune systems, and environmental factors may increase the risk of developing the infection.

Getting a Diagnosis

Signs and Symptoms of Acanthamoeba Keratitis

The most common signs and symptoms of AK include redness, pain, and blurred vision in the affected eye. Other symptoms may include light sensitivity, tearing, and a feeling of something in the eye. In some cases, the infection can cause a corneal ulcer, which is an open sore on the surface of the eye.

Diagnostic Tests for Acanthamoeba Keratitis

Diagnosis of AK is typically done through a combination of tests. These tests may include a slit-lamp examination, corneal scraping, and laboratory testing. During a slit-lamp examination, a doctor will use a microscope to look for signs of infection in the eye. A corneal scraping may also be done to collect a sample of the infected tissue for laboratory testing. The laboratory tests can help to identify the type of amoeba causing the infection.

Treatment of Acanthamoeba Keratitis

Treatment of AK typically involves a combination of medications, including antibiotics, antifungals, and anti-inflammatory drugs. In some cases, surgery may be necessary to remove the infected tissue. It is important to follow the doctor’s instructions carefully to ensure the infection is properly treated and to prevent further complications.

Prevention of Acanthamoeba Keratitis

The best way to prevent AK is to practice good hygiene when handling contact lenses. This includes washing your hands before handling lenses, using only sterile contact lens solutions, and replacing lenses as recommended by your doctor. It is also important to avoid swimming or showering while wearing contact lenses.

Questions for Your Doctor

Symptoms of Acanthamoeba Keratitis

The most common symptom of AK is pain in the eye, which can range from mild to severe. Other symptoms may include redness, tearing, blurred vision, sensitivity to light, and a feeling of something in the eye. If you experience any of these symptoms, it is important to see your doctor right away.

Diagnosis and Treatment of Acanthamoeba Keratitis

Your doctor will likely perform a physical exam and use a microscope to look for the presence of Acanthamoeba. If the infection is confirmed, your doctor may prescribe an antibiotic eye drop or ointment to treat the infection. In some cases, a corneal transplant may be necessary to restore vision.

Questions to Ask Your Doctor

When discussing your treatment options with your doctor, it is important to ask questions to ensure that you understand your diagnosis and treatment plan. Some questions you may want to ask include:

  • What is the best treatment for my condition?
  • What are the risks and benefits of the treatment?
  • What are the side effects of the treatment?
  • How long will the treatment take?
  • What can I do to prevent the infection from recurring?

It is also important to ask your doctor about any lifestyle changes you may need to make to reduce your risk of developing AK. These may include avoiding contact lenses, wearing protective eyewear when swimming, and avoiding contact with contaminated water.

Conclusion

Acanthamoeba keratitis is a serious eye infection that can cause vision loss if left untreated. If you have been diagnosed with AK, it is important to discuss your treatment options with your doctor. Be sure to ask questions to ensure that you understand your diagnosis and treatment plan, and to learn what lifestyle changes you may need to make to reduce your risk of developing AK.

Treatment

Antimicrobial Medications

The most common treatment for AK is a combination of antimicrobial medications. These medications are usually given as eye drops or ointments and may include antibiotics, antifungals, and/or antivirals. The medications are usually given for several weeks or months, depending on the severity of the infection.

Corticosteroids

Corticosteroids may also be prescribed to reduce inflammation and pain associated with AK. These medications are usually given as eye drops or ointments and may be used in combination with antimicrobial medications.

Surgery

In some cases, surgery may be necessary to remove the infected tissue. This may include corneal transplantation, which involves replacing the infected cornea with a healthy one.

Prevention

The best way to prevent AK is to practice good hygiene when handling contact lenses. This includes washing your hands before handling lenses, using only sterile contact lens solutions, and replacing lenses as recommended by your eye care provider.

Drugs & Medications

What Causes Acanthamoeba Keratitis?

AK is caused by a microscopic organism called Acanthamoeba. This organism is found in soil, water, and air, and can be transferred to the eye through contact lenses, swimming pools, hot tubs, and other sources of contaminated water. Poor contact lens hygiene, such as not cleaning or replacing lenses regularly, can also increase the risk of infection.

What Are the Symptoms of Acanthamoeba Keratitis?

The most common symptom of AK is severe eye pain. Other symptoms may include blurred vision, redness, light sensitivity, and a feeling of something in the eye. In some cases, the infection can cause scarring of the cornea, which can lead to vision loss.

How Is Acanthamoeba Keratitis Diagnosed?

AK is usually diagnosed through a combination of a physical exam, a slit-lamp exam, and a corneal scraping. During a physical exam, your doctor will look for signs of infection, such as redness, swelling, and discharge. A slit-lamp exam is a type of microscope that allows your doctor to get a closer look at the eye. A corneal scraping is a procedure in which a small sample of the cornea is taken and examined under a microscope for signs of infection.

How Is Acanthamoeba Keratitis Treated?

AK is usually treated with a combination of medications, including antibiotics, antifungals, and antivirals. In some cases, surgery may be necessary to remove the infected tissue. It is important to follow your doctor’s instructions carefully and take all medications as prescribed. In some cases, the infection can be difficult to treat and may require long-term treatment.

How Can Acanthamoeba Keratitis Be Prevented?

The best way to prevent AK is to practice good contact lens hygiene. This includes cleaning and replacing lenses regularly, avoiding swimming or hot tubs while wearing contacts, and avoiding tap water when cleaning lenses. It is also important to see your eye doctor regularly for checkups.

Diet

Diet Tips for Preventing Acanthamoeba Keratitis

A healthy diet is an important part of preventing AK. Eating a balanced diet that includes plenty of fruits, vegetables, and whole grains can help keep your eyes healthy and reduce your risk of infection. Here are some other diet tips to help you prevent AK:

  • Drink plenty of water. Staying hydrated helps keep your eyes healthy and can help reduce your risk of infection.
  • Eat foods rich in antioxidants. Antioxidants can help protect your eyes from damage caused by free radicals.
  • Eat foods rich in omega-3 fatty acids. Omega-3 fatty acids can help reduce inflammation and protect your eyes from damage.
  • Avoid processed foods. Processed foods are often high in sugar and unhealthy fats, which can increase your risk of infection.
  • Avoid foods that contain preservatives. Preservatives can increase your risk of infection.

By following these diet tips, you can help reduce your risk of developing Acanthamoeba Keratitis. Remember to talk to your doctor if you have any questions or concerns about your diet.

Lifestyle

Wear Protective Eyewear

Wearing protective eyewear, such as goggles or sunglasses, can help protect your eyes from coming into contact with Acanthamoeba. This is especially important if you are swimming in a lake, river, or other body of water, as Acanthamoeba is commonly found in these environments.

Avoid Contact Lenses

If you wear contact lenses, it is important to avoid wearing them in water or in any environment where Acanthamoeba may be present. This is because contact lenses can trap Acanthamoeba and increase your risk of infection. If you must wear contact lenses, make sure to follow the manufacturer’s instructions for cleaning and disinfecting them.

Practice Good Hygiene

Good hygiene is essential for preventing AK. Make sure to wash your hands regularly, especially after coming into contact with soil, dust, or water. Additionally, avoid touching your eyes with dirty hands or objects, as this can increase your risk of infection.

See Your Eye Doctor Regularly

It is important to see your eye doctor regularly for checkups and screenings. This will help ensure that any signs or symptoms of AK are caught early and treated promptly. Your eye doctor can also provide additional tips for preventing AK.

Conclusion

Acanthamoeba Keratitis is a serious eye infection that can cause permanent vision loss if left untreated. While there is no surefire way to prevent AK, there are some lifestyle tips that can help reduce your risk of infection. These include wearing protective eyewear, avoiding contact lenses, practicing good hygiene, and seeing your eye doctor regularly.