Non-Hodgkin Lymphoma

13 min read

Non-Hodgkin lymphoma (NHL) is a type of cancer that affects the lymphatic system, which is part of the body's immune system. It is a group of cancers that start in the lymphocytes, which are a type of white blood cell. NHL is the seventh most common cancer in the United States, and it affects both men and women.

Causes of Non-Hodgkin Lymphoma

The exact cause of NHL is unknown, but there are certain risk factors that may increase a person's chance of developing the disease. These include a weakened immune system, exposure to certain chemicals, and a family history of the disease.

Types of Non-Hodgkin Lymphoma

NHL is divided into two main types: B-cell lymphomas and T-cell lymphomas. B-cell lymphomas are the most common type of NHL, and they start in B-cells, which are a type of white blood cell. T-cell lymphomas start in T-cells, which are another type of white blood cell.

Diagnosis of Non-Hodgkin Lymphoma

NHL is usually diagnosed with a physical exam, blood tests, imaging tests, and a biopsy. A biopsy is a procedure in which a small sample of tissue is taken from the affected area and examined under a microscope.

Prognosis of Non-Hodgkin Lymphoma

The prognosis for NHL depends on the type and stage of the disease, as well as the person's age and overall health. Treatment options may include chemotherapy, radiation therapy, and immunotherapy.

Symptoms

Common Symptoms of Non-Hodgkin Lymphoma

The most common symptoms of non-Hodgkin lymphoma include:

  • Swollen lymph nodes in the neck, armpits, or groin
  • Unexplained weight loss
  • Fever
  • Night sweats
  • Fatigue
  • Itching
  • Abdominal pain or swelling
  • Chest pain or shortness of breath

Less Common Symptoms of Non-Hodgkin Lymphoma

Less common symptoms of non-Hodgkin lymphoma include:

  • Coughing
  • Difficulty swallowing
  • Pain in the abdomen or chest
  • Headaches
  • Bone pain
  • Joint pain
  • Skin rash or lumps
  • Nosebleeds

When to See a Doctor

If you experience any of the symptoms of non-Hodgkin lymphoma, it is important to see a doctor as soon as possible. Early diagnosis and treatment can help improve your chances of a successful outcome.

Take the Non-Hodgkin Lymphoma Assessment

Causes

Risk Factors for Non-Hodgkin Lymphoma

The following are some of the risk factors that may increase a person’s chances of developing NHL:

  • Age: NHL is more common in people over the age of 60.
  • Gender: Men are more likely to develop NHL than women.
  • Family history: Having a family member with NHL increases a person’s risk.
  • Weakened immune system: People with weakened immune systems, such as those with HIV/AIDS or those taking immunosuppressant drugs, are at higher risk.
  • Exposure to certain chemicals: Exposure to certain chemicals, such as herbicides and insecticides, may increase a person’s risk.
  • Infections: Certain infections, such as the Epstein-Barr virus, may increase a person’s risk.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop NHL. Many people with these risk factors never develop the disease.

Conclusion

Non-Hodgkin lymphoma is a serious condition that can be life-threatening if not treated. While the exact cause of NHL is unknown, there are certain factors that may increase a person’s risk of developing the disease. It is important to be aware of these risk factors and to talk to your doctor if you have any concerns.

Getting a Diagnosis

Diagnostic Tests for Non-Hodgkin Lymphoma

The first step in diagnosing NHL is to take a medical history and perform a physical exam. The doctor may also order blood tests, imaging tests, and biopsies to help diagnose the condition.

Blood Tests

Blood tests can help diagnose NHL by looking for certain markers in the blood. These markers can indicate the presence of cancer cells. The doctor may also order a complete blood count (CBC) to check for anemia, which can be a sign of NHL.

Imaging Tests

Imaging tests such as X-rays, CT scans, and MRIs can help the doctor to see if the lymph nodes are enlarged, which can be a sign of NHL. These tests can also help to determine the size and location of any tumors.

Biopsy

A biopsy is the only way to definitively diagnose NHL. During a biopsy, a small sample of tissue is taken from the affected area and examined under a microscope. This can help the doctor to determine the type and stage of the cancer.

Conclusion

Diagnosing NHL is an important step in the treatment process. The doctor may use a combination of blood tests, imaging tests, and biopsies to diagnose the condition. Early diagnosis and treatment can improve the chances of a successful outcome.

Questions for Your Doctor

Diagnosis and Staging

Your doctor will need to determine the type of Non-Hodgkin lymphoma you have and the stage of the disease. This will help them determine the best course of treatment. Ask your doctor to explain the diagnosis and staging process and what it means for your treatment.

Treatment Options

Your doctor will discuss the various treatment options available to you. This may include chemotherapy, radiation therapy, immunotherapy, or a combination of treatments. Ask your doctor to explain the risks and benefits of each treatment option and how they will affect your quality of life.

Side Effects

It is important to understand the potential side effects of the treatments you will be receiving. Ask your doctor to explain the common side effects and how they can be managed. Also, ask your doctor about any long-term side effects that may occur.

Follow-up Care

Your doctor will likely recommend follow-up care after your treatment is complete. Ask your doctor what type of follow-up care is recommended and how often it should be done. Also, ask your doctor about any lifestyle changes you should make to reduce your risk of recurrence.

Support Resources

Your doctor may be able to provide you with information about support resources in your area. Ask your doctor about any support groups or counseling services that may be available to you. Also, ask your doctor about any financial assistance programs that may be available.

Treatment

Chemotherapy

Chemotherapy is a common treatment for NHL. It involves using drugs to kill cancer cells. Chemotherapy can be used alone or in combination with other treatments, such as radiation therapy. It is usually given in cycles, with periods of rest in between.

Radiation Therapy

Radiation therapy is another treatment option for NHL. It involves using high-energy beams of radiation to kill cancer cells. Radiation therapy can be used alone or in combination with other treatments, such as chemotherapy. It is usually given in cycles, with periods of rest in between.

Immunotherapy

Immunotherapy is a type of treatment that uses the body’s own immune system to fight cancer. It can be used alone or in combination with other treatments, such as chemotherapy or radiation therapy. Immunotherapy can help the body recognize and attack cancer cells.

Targeted Therapy

Targeted therapy is a type of treatment that uses drugs to target specific molecules in cancer cells. It can be used alone or in combination with other treatments, such as chemotherapy or radiation therapy. Targeted therapy can help slow the growth of cancer cells and reduce the side effects of other treatments.

Stem Cell Transplant

A stem cell transplant is a type of treatment that involves replacing damaged or destroyed cells with healthy ones. It can be used to treat NHL that has not responded to other treatments. A stem cell transplant can help the body produce healthy cells and fight cancer.

Surgery

Surgery is sometimes used to treat NHL. It can be used to remove tumors or lymph nodes that are affected by the cancer. Surgery can also be used to remove organs that are affected by the cancer, such as the spleen or liver.

Clinical Trials

Clinical trials are research studies that test new treatments for NHL. They can help doctors learn more about the disease and develop new treatments. If you are interested in participating in a clinical trial, talk to your doctor about your options.

Drugs & Medications

Types of Drugs Used to Treat NHL

The type of drugs used to treat NHL will depend on the type and stage of the cancer. Commonly used drugs include:

  • Chemotherapy drugs: These drugs are used to kill cancer cells and can be given orally or intravenously.
  • Targeted therapy drugs: These drugs are designed to target specific cancer cells and can be given orally or intravenously.
  • Immunotherapy drugs: These drugs are designed to boost the body’s immune system and can be given orally or intravenously.
  • Hormone therapy drugs: These drugs are used to block the effects of hormones on cancer cells and can be given orally or intravenously.
  • Radiation therapy: This type of therapy uses high-energy beams to kill cancer cells and can be used in combination with other treatments.

Side Effects of NHL Drugs

The side effects of NHL drugs can vary depending on the type and dosage of the drug. Common side effects include:

  • Nausea and vomiting
  • Hair loss
  • Fatigue
  • Diarrhea
  • Mouth sores
  • Loss of appetite
  • Weight loss
  • Infection
  • Anemia
  • Low blood cell counts

Conclusion

Drugs are an important part of treating NHL. It is important to talk to your doctor about the potential side effects of the drugs you are taking and to follow their instructions for taking the drugs. With the right treatment plan, NHL can be managed and treated effectively.

Diet

Nutrients to Include in Your Diet

When it comes to eating for Non-Hodgkin lymphoma, it is important to focus on eating foods that are high in essential vitamins and minerals. Eating a variety of fruits, vegetables, whole grains, lean proteins, and healthy fats can help to ensure that your body is getting the nutrients it needs. Some of the most important nutrients to include in your diet are:

  • Vitamin A: Vitamin A is important for maintaining a healthy immune system and can help to reduce inflammation. Foods high in vitamin A include carrots, sweet potatoes, spinach, and kale.
  • Vitamin C: Vitamin C is an antioxidant that can help to protect the body from damage caused by free radicals. Foods high in vitamin C include oranges, strawberries, bell peppers, and broccoli.
  • Vitamin E: Vitamin E is an antioxidant that can help to protect the body from damage caused by free radicals. Foods high in vitamin E include almonds, sunflower seeds, and avocados.
  • Selenium: Selenium is an essential mineral that can help to boost the immune system and reduce inflammation. Foods high in selenium include Brazil nuts, tuna, and shrimp.
  • Zinc: Zinc is an essential mineral that can help to boost the immune system and reduce inflammation. Foods high in zinc include oysters, beef, and pumpkin seeds.

Foods to Avoid

In addition to eating foods that are high in essential vitamins and minerals, it is also important to avoid foods that can be harmful to your health. Some of the foods to avoid include:

  • Processed foods: Processed foods are high in sodium, sugar, and unhealthy fats, which can be harmful to your health. It is best to avoid processed foods as much as possible.
  • Sugary drinks: Sugary drinks are high in calories and can lead to weight gain. It is best to avoid sugary drinks and opt for water or unsweetened tea instead.
  • Alcohol: Alcohol can be harmful to your health and can interfere with your body’s ability to fight off infection. It is best to avoid alcohol as much as possible.

Conclusion

Eating a healthy diet is an important part of managing Non-Hodgkin lymphoma. Eating a variety of fruits, vegetables, whole grains, lean proteins, and healthy fats can help to ensure that your body is getting the nutrients it needs. It is also important to avoid processed foods, sugary drinks, and alcohol. By following a healthy diet, you can help to manage the symptoms of Non-Hodgkin lymphoma and improve your overall health.

Lifestyle

Eat a Healthy Diet

Eating a healthy diet is important for everyone, but especially for those with Non-Hodgkin lymphoma. Eating a balanced diet with plenty of fruits, vegetables, and lean proteins can help you maintain your strength and energy levels. It is also important to limit your intake of processed and sugary foods, as these can be detrimental to your health.

Get Regular Exercise

Exercise is important for everyone, but especially for those with Non-Hodgkin lymphoma. Regular exercise can help you maintain your strength and energy levels, as well as reduce stress and anxiety. It is important to talk to your doctor before starting any exercise program, as some activities may be too strenuous for you.

Get Enough Sleep

Getting enough sleep is essential for everyone, but especially for those with Non-Hodgkin lymphoma. Getting enough sleep can help you maintain your strength and energy levels, as well as reduce stress and anxiety. It is important to talk to your doctor about how much sleep you should be getting each night.

Manage Stress

Stress can have a negative impact on your health, so it is important to find ways to manage it. Taking time for yourself, engaging in relaxation activities, and talking to a therapist can all help you manage stress. It is also important to talk to your doctor about any stress-related symptoms you may be experiencing.

Stay Connected

Staying connected with family and friends can help you cope with the challenges of Non-Hodgkin lymphoma. Talking to people who understand what you are going through can be a great source of support. It is also important to stay connected with your healthcare team to ensure you are getting the best care possible.