Laryngopharyngeal Reflux

11 min read

Laryngopharyngeal reflux (LPR) is a condition in which stomach acid backs up into the throat and larynx, causing irritation and inflammation. It is also known as silent reflux because it often does not cause any symptoms. LPR is different from gastroesophageal reflux disease (GERD), which is a more severe form of reflux that can cause heartburn and other symptoms.

Causes of Laryngopharyngeal Reflux

LPR is caused by a malfunction of the lower esophageal sphincter (LES), which is the muscle that separates the stomach from the esophagus. Normally, the LES opens to allow food to pass into the stomach and then closes to prevent stomach acid from flowing back up into the esophagus. In people with LPR, the LES does not close properly, allowing stomach acid to flow back up into the throat and larynx.

Risk Factors for Laryngopharyngeal Reflux

Certain factors can increase the risk of developing LPR, including:

  • Being overweight or obese
  • Smoking
  • Eating large meals
  • Eating certain foods, such as spicy or acidic foods
  • Drinking alcohol
  • Stress
  • Certain medications, such as calcium channel blockers and nonsteroidal anti-inflammatory drugs (NSAIDs)

Diagnosis of Laryngopharyngeal Reflux

LPR is often difficult to diagnose because it does not usually cause any symptoms. If symptoms do occur, they may include:

  • Hoarseness
  • Chronic cough
  • Sore throat
  • Difficulty swallowing
  • Post-nasal drip
  • Bad breath

If your doctor suspects that you have LPR, they may order tests to confirm the diagnosis. These tests may include an endoscopy, in which a thin tube with a camera is inserted down the throat to examine the larynx and esophagus, or a pH test, in which a small tube is inserted into the nose to measure the acidity of the stomach contents.

Complications of Laryngopharyngeal Reflux

If left untreated, LPR can lead to complications, such as:

  • Chronic laryngitis
  • Vocal cord nodules
  • Esophagitis
  • Barrett's esophagus
  • Esophageal stricture

Prevention of Laryngopharyngeal Reflux

There are several lifestyle changes that can help prevent LPR, such as:

  • Maintaining a healthy weight
  • Avoiding large meals
  • Avoiding certain foods, such as spicy or acidic foods
  • Avoiding alcohol and smoking
  • Elevating the head of the bed
  • Avoiding lying down after eating
  • Avoiding tight-fitting clothing
Take the Laryngopharyngeal Reflux Assessment

Symptoms

Common Symptoms of Laryngopharyngeal Reflux

  • Sore throat
  • Hoarseness
  • Chronic cough
  • Difficulty swallowing
  • A sensation of a lump in the throat
  • Asthma-like symptoms

Less Common Symptoms of Laryngopharyngeal Reflux

  • Chronic throat clearing
  • A sensation of mucus or phlegm in the throat
  • Post-nasal drip
  • Bad breath
  • Hoarse voice
  • Wheezing

Diagnosing Laryngopharyngeal Reflux

If you are experiencing any of the symptoms of LPR, it is important to see your doctor for a proper diagnosis. Your doctor may recommend a series of tests, such as an endoscopy, to determine if you have LPR. Treatment for LPR may include lifestyle changes, such as avoiding certain foods and drinks, and medications to reduce stomach acid.

Causes

Diet

Certain foods and drinks can increase the risk of LPR. These include acidic foods such as citrus fruits, tomatoes, and vinegar; spicy foods; caffeine; and alcohol. Eating large meals or eating close to bedtime can also increase the risk of LPR.

Smoking

Smoking can irritate the throat and increase the risk of LPR. It can also weaken the lower esophageal sphincter, which is the muscle that helps keep stomach acid in the stomach.

Obesity

Being overweight or obese can increase the risk of LPR. This is because excess weight can put pressure on the stomach, which can cause stomach acid to back up into the throat.

Pregnancy

Pregnancy can increase the risk of LPR due to the increased levels of hormones in the body. These hormones can relax the lower esophageal sphincter, allowing stomach acid to back up into the throat.

Medications

Certain medications can increase the risk of LPR. These include calcium channel blockers, sedatives, and antidepressants. It is important to talk to your doctor if you are taking any of these medications and experiencing symptoms of LPR.

Getting a Diagnosis

Endoscopy

An endoscopy is a procedure in which a thin, flexible tube with a camera is inserted through the mouth and into the throat and larynx. This allows the doctor to see any signs of inflammation or irritation caused by LPR. The doctor may also take a biopsy, or small sample of tissue, to be examined in a lab.

pH Monitoring

pH monitoring is a test that measures the amount of acid in the throat and larynx. During the test, a small tube is inserted through the nose and into the throat. The tube is connected to a monitor that records the pH levels over a 24-hour period. If the pH levels are consistently higher than normal, it may indicate LPR.

Imaging Tests

Imaging tests, such as X-rays, CT scans, and MRIs, can be used to look for any structural abnormalities in the throat and larynx that may be causing LPR. These tests can also help rule out other conditions that may be causing similar symptoms.

Treatment

Once LPR is diagnosed, treatment will depend on the severity of the condition. Treatment may include lifestyle changes, such as avoiding certain foods and drinks, and medications to reduce stomach acid. In some cases, surgery may be necessary to correct any structural abnormalities in the throat and larynx.

Questions for Your Doctor

Symptoms

Be sure to tell your doctor about any symptoms you are experiencing, such as:

  • Hoarseness
  • Chronic cough
  • Sore throat
  • Difficulty swallowing
  • Post-nasal drip
  • Heartburn
  • Bad breath

Medical History

Your doctor will also want to know about your medical history, including any medications you are taking and any allergies you have. It is also important to tell your doctor if you have any family history of LPR or other digestive disorders.

Lifestyle Habits

Your doctor may also ask about your lifestyle habits, such as your diet, exercise routine, and smoking and drinking habits. These can all affect your risk of developing LPR.

Treatment Options

Your doctor will discuss treatment options with you, which may include lifestyle changes, medications, or surgery. Be sure to ask any questions you have about the treatment options and their potential side effects.

Treatment

Lifestyle Changes

Making certain lifestyle changes can help reduce the symptoms of LPR. These include avoiding foods and beverages that can trigger reflux, such as spicy foods, caffeine, and alcohol. Eating smaller meals more frequently can also help, as can avoiding eating close to bedtime. Additionally, quitting smoking and losing weight can help reduce the symptoms of LPR.

Medications

There are a number of medications that can be used to treat LPR. These include antacids, H2 blockers, and proton pump inhibitors. Antacids can help neutralize stomach acid, while H2 blockers and proton pump inhibitors can help reduce the amount of acid produced by the stomach. Additionally, medications such as prokinetics can help strengthen the lower esophageal sphincter, which can help prevent reflux.

Surgery

In some cases, surgery may be necessary to treat LPR. The most common type of surgery is fundoplication, which involves wrapping the upper part of the stomach around the lower esophageal sphincter to help prevent reflux. Other types of surgery, such as endoscopic procedures, may also be used to treat LPR.

Alternative Treatments

There are also a number of alternative treatments that may be used to treat LPR. These include acupuncture, herbal remedies, and dietary supplements. Additionally, some people find that relaxation techniques, such as yoga and meditation, can help reduce the symptoms of LPR.

Drugs & Medications

What Causes Laryngopharyngeal Reflux?

Laryngopharyngeal reflux is caused by a malfunction of the lower esophageal sphincter (LES). The LES is a muscle at the bottom of the esophagus that normally opens and closes to allow food to pass from the esophagus into the stomach. When the LES does not close properly, stomach acid can back up into the throat and larynx, causing irritation and inflammation.

Treatment for Laryngopharyngeal Reflux

Treatment for LPR typically involves lifestyle changes, such as avoiding foods that trigger reflux, eating smaller meals, and avoiding eating late at night. In addition, medications may be prescribed to reduce stomach acid production and help the LES close properly. These medications include proton pump inhibitors (PPIs) and H2 blockers. Surgery may also be recommended in some cases.

Conclusion

Laryngopharyngeal reflux is a condition in which stomach acid backs up into the throat and larynx, causing irritation and inflammation. Treatment typically involves lifestyle changes and medications to reduce stomach acid production and help the LES close properly. Surgery may also be recommended in some cases. If you think you may have LPR, it is important to speak to your doctor to determine the best course of treatment.

Diet

What to Eat

When living with LPR, it is important to eat foods that are easy to digest and do not cause irritation. Some foods that may be beneficial include:

  • Low-fat dairy products, such as yogurt and cottage cheese
  • Fruits, such as apples, bananas, and melons
  • Vegetables, such as broccoli, carrots, and spinach
  • Whole grains, such as oatmeal, quinoa, and brown rice
  • Lean proteins, such as fish, chicken, and tofu

It is also important to drink plenty of water throughout the day to help keep the throat and stomach hydrated.

What to Avoid

Certain foods and drinks can worsen the symptoms of LPR. It is best to avoid the following:

  • Caffeinated beverages, such as coffee, tea, and soda
  • Alcoholic beverages
  • Spicy foods
  • Acidic foods, such as citrus fruits and tomatoes
  • Fatty and fried foods
  • Garlic and onions
  • Chocolate

It is also important to avoid eating large meals, as this can cause the stomach to produce more acid. Eating smaller, more frequent meals can help reduce symptoms.

Conclusion

Living with laryngopharyngeal reflux can be difficult, but making dietary changes can help reduce symptoms. Eating foods that are easy to digest and avoiding foods that can worsen symptoms can help keep the throat and stomach healthy. It is also important to drink plenty of water throughout the day.

Lifestyle

Eat Smaller Meals

Eating smaller meals throughout the day can help reduce the amount of stomach acid that backs up into the throat. Eating smaller meals also helps to reduce the amount of time that stomach acid is in contact with the throat, which can help reduce irritation and inflammation.

Avoid Trigger Foods

Certain foods can trigger LPR symptoms, such as spicy foods, acidic foods, and fatty foods. Avoiding these foods can help reduce your risk of developing LPR. Additionally, eating a balanced diet that is rich in fruits, vegetables, and whole grains can help reduce your risk of developing LPR.

Avoid Smoking and Alcohol

Smoking and alcohol can both irritate the throat and increase your risk of developing LPR. If you smoke, quitting can help reduce your risk of developing LPR. Additionally, avoiding alcohol can help reduce your risk of developing LPR.

Maintain a Healthy Weight

Being overweight or obese can increase your risk of developing LPR. Maintaining a healthy weight can help reduce your risk of developing LPR. Additionally, exercising regularly can help you maintain a healthy weight and reduce your risk of developing LPR.

Avoid Tight Clothing

Tight clothing can put pressure on the stomach, which can cause stomach acid to back up into the throat. Avoiding tight clothing can help reduce your risk of developing LPR.

Elevate Your Head While Sleeping

Elevating your head while sleeping can help reduce the amount of stomach acid that backs up into the throat. You can do this by using extra pillows or a wedge pillow to elevate your head while sleeping.

See Your Doctor

If you are experiencing symptoms of LPR, it is important to see your doctor. Your doctor can help diagnose your condition and recommend treatment options to help reduce your symptoms.