Hyperandrogenism

10 min read

Hyperandrogenism is a medical condition in which a person has higher than normal levels of androgens, which are hormones that are typically found in higher concentrations in males than in females. It can affect both men and women, and can be caused by a variety of factors, including genetic disorders, endocrine disorders, and certain medications.

Causes of Hyperandrogenism

Hyperandrogenism can be caused by a variety of factors, including genetic disorders, endocrine disorders, and certain medications. Genetic disorders that can cause hyperandrogenism include congenital adrenal hyperplasia, polycystic ovary syndrome, and androgen insensitivity syndrome. Endocrine disorders that can cause hyperandrogenism include Cushing's syndrome, hyperprolactinemia, and hyperthyroidism. Certain medications, such as anabolic steroids, can also cause hyperandrogenism.

Diagnosis of Hyperandrogenism

Hyperandrogenism is typically diagnosed through a physical examination and laboratory tests. During the physical examination, the doctor will look for signs of hyperandrogenism, such as acne, hirsutism, and male-pattern baldness. Laboratory tests can measure the levels of androgens in the blood, as well as other hormones that can be affected by hyperandrogenism.

Complications of Hyperandrogenism

Hyperandrogenism can cause a variety of complications, including infertility, menstrual irregularities, and psychological issues. It can also increase the risk of certain health conditions, such as diabetes, heart disease, and high blood pressure.

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Symptoms

  • Acne
  • Excess body hair
  • Male-pattern baldness
  • Deepening of the voice
  • Enlargement of the clitoris
  • Irregular or absent menstrual periods
  • Weight gain
  • Fatigue
  • Headaches
  • Mood swings

If you are experiencing any of these symptoms, it is important to speak to your doctor. They can help diagnose the condition and provide treatment options.

Causes

Genetic Factors

Hyperandrogenism can be caused by genetic factors, such as an inherited gene mutation. In some cases, the condition is caused by an inherited disorder, such as congenital adrenal hyperplasia or polycystic ovary syndrome (PCOS). These disorders can cause the body to produce too much of certain hormones, leading to an increase in androgen levels.

Hormonal Imbalances

Hormonal imbalances can also cause hyperandrogenism. For example, an overproduction of luteinizing hormone (LH) can lead to an increase in androgen production. Other hormonal imbalances, such as an overproduction of prolactin or an underproduction of sex hormone-binding globulin (SHBG), can also contribute to hyperandrogenism.

Medications

Certain medications can also cause hyperandrogenism. For example, some medications used to treat depression, such as tricyclic antidepressants, can lead to an increase in androgen levels. Other medications, such as glucocorticoids, can also cause hyperandrogenism.

Obesity

Obesity can also contribute to hyperandrogenism. Excess body fat can lead to an increase in androgen production, as well as an increase in the conversion of androgens to estrogens. This can lead to an imbalance in hormone levels, which can cause a variety of symptoms.

Stress

Stress can also contribute to hyperandrogenism. Stress can lead to an increase in cortisol levels, which can lead to an increase in androgen production. This can cause a variety of physical and psychological symptoms.

Getting a Diagnosis

Medical History and Physical Exam

The first step in diagnosing hyperandrogenism is to take a detailed medical history and perform a physical exam. Your doctor will ask about your symptoms, family history, and any medications you are taking. During the physical exam, your doctor will look for signs of hyperandrogenism, such as acne, hirsutism, and changes in the skin or hair. Your doctor may also order blood tests to check your hormone levels.

Hormone Tests

Hormone tests are used to measure the levels of androgens in the body. These tests can help determine if there is an excess of androgens and can help identify the cause of the condition. Common tests include testosterone, dehydroepiandrosterone sulfate (DHEAS), and androstenedione. Your doctor may also order tests to measure other hormones, such as luteinizing hormone (LH) and follicle-stimulating hormone (FSH).

Imaging Tests

Imaging tests, such as ultrasound or MRI, may be used to look for any abnormalities in the ovaries or adrenal glands. These tests can help identify any tumors or cysts that may be causing the excess of androgens. Your doctor may also order a CT scan or MRI to look for any other abnormalities in the body.

Genetic Tests

Genetic tests may be used to look for any genetic mutations that may be causing the condition. These tests can help identify any inherited conditions that may be causing the excess of androgens. Your doctor may also order genetic tests to look for any other genetic abnormalities that may be causing the condition.

Conclusion

Diagnosing hyperandrogenism can be a complex process, as there are many potential causes and a variety of tests that may be used to make a diagnosis. Your doctor will take a detailed medical history and perform a physical exam to look for signs of hyperandrogenism. Hormone tests, imaging tests, and genetic tests may also be used to help diagnose the condition. If you think you may have hyperandrogenism, talk to your doctor about the best way to diagnose and treat the condition.

Questions for Your Doctor

Questions to Ask Your Doctor

  • What tests do I need to diagnose hyperandrogenism?
  • What treatments are available for hyperandrogenism?
  • What lifestyle changes can I make to help manage my symptoms?
  • Are there any long-term risks associated with hyperandrogenism?
  • Are there any other conditions that could be causing my symptoms?

Things to Tell Your Doctor

  • When did you first start noticing symptoms?
  • What medications or supplements are you currently taking?
  • Do you have a family history of hyperandrogenism?
  • Do you have any other medical conditions?
  • Are you currently under any stress?

Talking to your doctor about hyperandrogenism can help you get the treatment you need to manage your symptoms. Be sure to ask questions and provide your doctor with as much information as possible.

Treatment

Medications

One of the most common treatments for hyperandrogenism is medication. Birth control pills are often prescribed to help regulate hormones and reduce the symptoms of hyperandrogenism. Other medications, such as spironolactone, can also be used to reduce androgen levels. In some cases, medications such as metformin may be prescribed to help regulate insulin levels.

Lifestyle Changes

Making lifestyle changes can also help reduce the symptoms of hyperandrogenism. Eating a healthy diet, exercising regularly, and reducing stress can all help to regulate hormones and reduce symptoms. Additionally, avoiding certain triggers, such as dairy and sugar, can help to reduce symptoms.

Surgery

In some cases, surgery may be recommended to treat hyperandrogenism. Surgery can be used to remove ovarian cysts or to reduce the size of the ovaries. In some cases, surgery may also be used to remove excess body hair.

Alternative Treatments

In addition to traditional treatments, there are also alternative treatments that may be used to help manage the symptoms of hyperandrogenism. Herbal supplements, acupuncture, and yoga can all be used to help regulate hormones and reduce symptoms. It is important to speak to a doctor before trying any alternative treatments.

Drugs & Medications

Drugs for Hyperandrogenism

There are several drugs that can be used to treat hyperandrogenism. These include oral contraceptives, anti-androgens, and insulin sensitizers. Oral contraceptives are often used to regulate menstrual cycles and reduce the production of androgens. Anti-androgens are drugs that block the action of androgens, which can help reduce symptoms such as hirsutism and acne. Insulin sensitizers are drugs that help the body use insulin more effectively, which can help reduce androgen levels.

Conclusion

Hyperandrogenism is a medical condition that can cause a variety of symptoms, including acne, hirsutism, and infertility. There are several drugs that can be used to treat hyperandrogenism, including oral contraceptives, anti-androgens, and insulin sensitizers. It is important to speak to a doctor to determine the best treatment plan for your individual needs.

Diet

What to Eat

A healthy diet for hyperandrogenism should include plenty of fruits, vegetables, whole grains, and lean proteins. Eating a variety of these foods can help provide the body with the nutrients it needs to function properly. Additionally, it is important to drink plenty of water to stay hydrated. Here are some specific foods to include in your diet:

  • Fruits: Apples, oranges, bananas, berries, and other fresh fruits
  • Vegetables: Leafy greens, broccoli, carrots, peppers, and other vegetables
  • Whole grains: Oats, quinoa, brown rice, and other whole grains
  • Lean proteins: Chicken, fish, tofu, and other lean proteins
  • Healthy fats: Avocados, nuts, and seeds

What to Avoid

In addition to eating a healthy diet, it is important to avoid certain foods that can worsen the symptoms of hyperandrogenism. These include processed foods, sugary drinks, and foods high in saturated fat. Here are some specific foods to avoid:

  • Processed foods: Packaged snacks, frozen meals, and other processed foods
  • Sugary drinks: Soda, energy drinks, and other sugary beverages
  • Foods high in saturated fat: Fried foods, red meat, and other foods high in saturated fat

Conclusion

Eating a healthy diet can help manage the symptoms of hyperandrogenism. It is important to include plenty of fruits, vegetables, whole grains, and lean proteins in your diet. Additionally, it is important to avoid processed foods, sugary drinks, and foods high in saturated fat. By following these dietary guidelines, you can help keep your androgen levels in check.

Lifestyle

Eat a Balanced Diet

Eating a balanced diet is important for managing hyperandrogenism. Eating a variety of fruits, vegetables, whole grains, and lean proteins can help keep your hormones in balance. Avoid processed foods, sugar, and saturated fats, as these can increase androgen levels. Additionally, make sure to drink plenty of water to stay hydrated.

Exercise Regularly

Regular exercise can help reduce androgen levels and improve overall health. Aim for at least 30 minutes of moderate-intensity exercise, such as walking, jogging, or swimming, five days a week. Additionally, strength training can help reduce androgen levels and improve muscle tone.

Reduce Stress

Stress can increase androgen levels, so it is important to find ways to reduce stress. Try activities such as yoga, meditation, or deep breathing to help relax. Additionally, make sure to get enough sleep and take time for yourself to relax and unwind.

Talk to Your Doctor

If lifestyle changes are not enough to manage your symptoms, talk to your doctor. They may recommend medications or other treatments to help manage your condition.