Colorectal Cancer

14 min read

Colorectal cancer is a type of cancer that affects the colon and rectum. It is the third most common type of cancer in the United States, and the second leading cause of cancer-related deaths. It is estimated that in 2020, there will be over 140,000 new cases of colorectal cancer in the United States.

Risk Factors

There are several risk factors associated with colorectal cancer, including age, family history, lifestyle, and diet. People over the age of 50 are at an increased risk of developing colorectal cancer, as are those with a family history of the disease. Additionally, people who smoke, are overweight, or have a diet high in red or processed meats are at an increased risk.

Screening and Prevention

Screening for colorectal cancer is important for early detection and treatment. The American Cancer Society recommends that people at average risk begin screening at age 45. People at higher risk may need to begin screening earlier. Additionally, there are several lifestyle changes that can help reduce the risk of colorectal cancer, such as maintaining a healthy weight, exercising regularly, and eating a diet high in fruits and vegetables.

Diagnosis and Treatment

If colorectal cancer is suspected, a doctor may order a variety of tests to confirm the diagnosis. These tests may include a colonoscopy, a biopsy, or imaging tests. Treatment for colorectal cancer may include surgery, chemotherapy, radiation therapy, or a combination of these treatments.

Symptoms

Changes in Bowel Habits

One of the most common symptoms of colorectal cancer is a change in bowel habits. This can include having diarrhea, constipation, or a change in the consistency of your stool. You may also experience a feeling of incomplete evacuation after a bowel movement.

Blood in the Stool

Another symptom of colorectal cancer is the presence of blood in the stool. This can be either bright red or dark in color. It is important to note that this symptom can also be caused by other conditions, so it is important to see a doctor if you experience this symptom.

Abdominal Pain

Abdominal pain is another symptom of colorectal cancer. This can range from a dull ache to sharp pains. It is important to note that this symptom can also be caused by other conditions, so it is important to see a doctor if you experience this symptom.

Unexplained Weight Loss

Unexplained weight loss is another symptom of colorectal cancer. This can be caused by the cancer itself or by the treatments used to treat it. If you experience unexplained weight loss, it is important to see a doctor.

Fatigue

Fatigue is another symptom of colorectal cancer. This can be caused by the cancer itself or by the treatments used to treat it. If you experience unexplained fatigue, it is important to see a doctor.

Conclusion

Colorectal cancer is a serious condition that can be life-threatening if not caught early. It is important to be aware of the symptoms so that it can be caught early and treated. If you experience any of the symptoms listed above, it is important to see a doctor.

Take the Colorectal Cancer Assessment

Causes

Age

Age is one of the most significant risk factors for colorectal cancer. The risk of developing colorectal cancer increases with age, with most cases occurring in people over the age of 50. People over the age of 50 should be screened regularly for colorectal cancer.

Family History

Having a family history of colorectal cancer or polyps increases a person’s risk of developing the disease. People with a first-degree relative (parent, sibling, or child) who has had colorectal cancer are at an increased risk of developing the disease.

Diet

A diet high in red and processed meats, such as hot dogs and bacon, has been linked to an increased risk of colorectal cancer. Eating a diet high in fruits, vegetables, and whole grains can help reduce the risk of colorectal cancer.

Smoking

Smoking has been linked to an increased risk of colorectal cancer. People who smoke are more likely to develop colorectal cancer than those who do not smoke.

Obesity

Being overweight or obese increases a person’s risk of developing colorectal cancer. People who are overweight or obese should talk to their doctor about ways to reduce their risk of colorectal cancer.

Alcohol

Drinking alcohol has been linked to an increased risk of colorectal cancer. People who drink alcohol should limit their intake to no more than one drink per day for women and two drinks per day for men.

Lack of Exercise

People who do not get enough physical activity are at an increased risk of developing colorectal cancer. People should aim to get at least 30 minutes of moderate physical activity, such as walking, five days a week.

Chronic Inflammatory Diseases

People with chronic inflammatory diseases, such as Crohn’s disease and ulcerative colitis, are at an increased risk of developing colorectal cancer. People with these conditions should talk to their doctor about ways to reduce their risk of colorectal cancer.

Getting a Diagnosis

Colonoscopy

A colonoscopy is a procedure that allows a doctor to look inside the colon and rectum for signs of cancer. During the procedure, a thin, flexible tube with a camera on the end is inserted into the rectum. The doctor can then look for any abnormal growths or polyps that may be cancerous. If any are found, a biopsy can be taken to confirm the diagnosis.

Sigmoidoscopy

A sigmoidoscopy is similar to a colonoscopy, but it only examines the lower part of the colon. During the procedure, a thin, flexible tube with a camera on the end is inserted into the rectum. The doctor can then look for any abnormal growths or polyps that may be cancerous. If any are found, a biopsy can be taken to confirm the diagnosis.

Stool Tests

Stool tests are used to look for blood in the stool, which can be a sign of colorectal cancer. The most common type of stool test is the fecal occult blood test (FOBT). During this test, a sample of stool is collected and tested for the presence of blood. If blood is found, further testing may be needed to determine the cause.

Imaging Tests

Imaging tests, such as X-rays, CT scans, and MRI scans, can be used to look for tumors or other abnormalities in the colon and rectum. These tests can help the doctor determine the size and location of any tumors that may be present.

Biopsy

A biopsy is a procedure in which a small sample of tissue is taken from the colon or rectum and examined under a microscope. This can help the doctor determine if the tissue is cancerous. If cancer is found, further testing may be needed to determine the stage of the cancer.

Questions for Your Doctor

Risk Factors

Your doctor can help you understand your risk factors for colorectal cancer. Risk factors include age, family history, lifestyle, and certain medical conditions. Your doctor can help you understand your risk and what you can do to reduce it.

Screening Tests

Your doctor can help you decide which screening tests are right for you. Screening tests can help detect colorectal cancer early, when it is most treatable. Your doctor can help you understand the benefits and risks of different screening tests.

Treatment Options

If you are diagnosed with colorectal cancer, your doctor can help you understand your treatment options. Treatment options may include surgery, chemotherapy, radiation therapy, and targeted therapy. Your doctor can help you understand the benefits and risks of each treatment option.

Side Effects

Your doctor can help you understand the side effects of treatment. Side effects may include fatigue, nausea, hair loss, and changes in appetite. Your doctor can help you manage side effects and find ways to cope.

Follow-up Care

Your doctor can help you understand the importance of follow-up care. Follow-up care may include regular check-ups, imaging tests, and blood tests. Your doctor can help you understand the importance of follow-up care and how to stay on track.

Treatment

Surgery

Surgery is the most common treatment for colorectal cancer. The goal of surgery is to remove the cancerous tumor and any nearby lymph nodes. Depending on the stage of the cancer, the surgeon may also remove part or all of the colon or rectum. In some cases, the surgeon may also need to remove other organs, such as the bladder or ovaries.

Chemotherapy

Chemotherapy is a type of treatment that uses drugs to kill cancer cells. It is often used in combination with surgery to reduce the risk of the cancer coming back. Chemotherapy is usually given in cycles, with each cycle lasting several weeks. The side effects of chemotherapy can vary, but they may include fatigue, nausea, hair loss, and an increased risk of infection.

Radiation Therapy

Radiation therapy is a type of treatment that uses high-energy beams to kill cancer cells. It is often used in combination with chemotherapy to reduce the risk of the cancer coming back. Radiation therapy is usually given in cycles, with each cycle lasting several weeks. The side effects of radiation therapy can vary, but they may include fatigue, skin irritation, and an increased risk of infection.

Targeted Therapy

Targeted therapy is a type of treatment that uses drugs to target specific molecules in cancer cells. It is often used in combination with chemotherapy and radiation therapy to reduce the risk of the cancer coming back. Targeted therapy is usually given in cycles, with each cycle lasting several weeks. The side effects of targeted therapy can vary, but they may include fatigue, nausea, and an increased risk of infection.

Immunotherapy

Immunotherapy is a type of treatment that uses the body’s own immune system to fight cancer cells. It is often used in combination with chemotherapy and radiation therapy to reduce the risk of the cancer coming back. Immunotherapy is usually given in cycles, with each cycle lasting several weeks. The side effects of immunotherapy can vary, but they may include fatigue, nausea, and an increased risk of infection.

Conclusion

Colorectal cancer is a serious condition, but there are a variety of treatments available. Surgery is the most common treatment, but chemotherapy, radiation therapy, targeted therapy, and immunotherapy are also options. The type of treatment will depend on the stage of the cancer and the individual patient. It is important to talk to your doctor about the best treatment option for you.

Drugs & Medications

Types of Drugs Used to Treat Colorectal Cancer

The type of drug used to treat colorectal cancer will depend on the stage of the cancer and the individual patient. Commonly used drugs include:

  • Chemotherapy drugs, such as 5-fluorouracil (5-FU), capecitabine, and oxaliplatin
  • Targeted therapy drugs, such as cetuximab, panitumumab, and bevacizumab
  • Immunotherapy drugs, such as pembrolizumab and nivolumab
  • Hormonal therapy drugs, such as tamoxifen and goserelin

How Do These Drugs Work?

Chemotherapy drugs work by killing cancer cells or stopping them from growing and dividing. Targeted therapy drugs work by targeting specific molecules on the surface of cancer cells, which can help to slow the growth of the cancer. Immunotherapy drugs work by stimulating the body’s own immune system to fight the cancer. Hormonal therapy drugs work by blocking the hormones that can cause cancer cells to grow.

Side Effects of Drugs Used to Treat Colorectal Cancer

The side effects of the drugs used to treat colorectal cancer can vary depending on the type of drug and the individual patient. Common side effects of chemotherapy drugs include nausea, vomiting, hair loss, and fatigue. Common side effects of targeted therapy drugs include skin rash, diarrhea, and fatigue. Common side effects of immunotherapy drugs include fatigue, rash, and nausea. Common side effects of hormonal therapy drugs include hot flashes, nausea, and weight gain.

Conclusion

Colorectal cancer is a serious condition that can be treated with a variety of drugs. These drugs can help to slow the growth of the cancer or even shrink the tumor. However, it is important to be aware of the potential side effects of these drugs, as they can vary depending on the type of drug and the individual patient.

Diet

Fiber

Fiber is an important part of any healthy diet, and it can also help reduce your risk of colorectal cancer. Eating foods that are high in fiber, such as whole grains, fruits, and vegetables, can help keep your digestive system healthy and reduce your risk of developing colorectal cancer. Aim to get at least 25 grams of fiber per day.

Low-Fat Diet

Eating a low-fat diet can also help reduce your risk of colorectal cancer. Eating foods that are high in fat, such as red meat, processed meats, and full-fat dairy products, can increase your risk of developing colorectal cancer. Aim to limit your intake of these foods and opt for leaner proteins, such as fish, poultry, and beans, instead.

Fruits and Vegetables

Eating plenty of fruits and vegetables is an important part of any healthy diet, and it can also help reduce your risk of colorectal cancer. Fruits and vegetables are rich in vitamins, minerals, and antioxidants, which can help protect your cells from damage that can lead to cancer. Aim to eat at least five servings of fruits and vegetables per day.

Conclusion

Eating a healthy diet that is rich in fiber, low in fat, and includes plenty of fruits and vegetables can help reduce your risk of developing colorectal cancer. Making these dietary changes can help you maintain a healthy weight, keep your digestive system healthy, and reduce your risk of developing this type of cancer.

Lifestyle

Eat a Healthy Diet

Eating a healthy diet is one of the best ways to reduce your risk of colorectal cancer. Eating plenty of fruits, vegetables, and whole grains can help reduce your risk. Additionally, limiting your intake of red and processed meats can also help reduce your risk. Eating a healthy diet can also help you maintain a healthy weight, which is another important factor in reducing your risk of colorectal cancer.

Exercise Regularly

Regular physical activity is another important factor in reducing your risk of colorectal cancer. Aim for at least 30 minutes of moderate-intensity physical activity on most days of the week. This can include activities such as walking, jogging, swimming, or biking. Regular physical activity can also help you maintain a healthy weight, which can further reduce your risk.

Avoid Smoking and Excessive Alcohol Consumption

Smoking and excessive alcohol consumption can increase your risk of colorectal cancer. If you smoke, quitting is one of the best things you can do to reduce your risk. Additionally, limiting your alcohol consumption to no more than one drink per day for women and two drinks per day for men can help reduce your risk.

Get Screened Regularly

Getting screened regularly is one of the best ways to detect colorectal cancer early. The American Cancer Society recommends that adults aged 45 and older get screened for colorectal cancer. Talk to your doctor about which screening test is right for you.

Conclusion

Making lifestyle changes can help reduce your risk of colorectal cancer. Eating a healthy diet, exercising regularly, avoiding smoking and excessive alcohol consumption, and getting screened regularly are all important steps you can take to reduce your risk. Talk to your doctor about other ways you can reduce your risk of colorectal cancer.